Protein Modification Reagents
Medchemexpress LLC HY-112496 100mg Medchemexpress, Cl-C6-PEG4-O-CH2COOH CAS:1799506-30-1 Purity:>98%
Medchemexpress, HY-112496 100mg Cl-C6-PEG4-O-CH2COOH CAS:1799506-30-1 Cl-C6-PEG4-O-CH2COOH (PROTAC Linker 4) is a PEG-based PROTAC linker can be used in the synthesis of chloroalkane-containing PROTACs (HaloPROTACs). Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC Dspe-peg-cooh, mw 2000 | 1403744-37-5 | 100.0% | 2000 Da | C50H94N2NaO14P | 1 MG
DSPE-PEG-COOH (MW 2000) is a PEGylated phospholipid composed of distearoylphosphatidylethanolamine linked to an approximately 2,000 Da polyethylene glycol chain terminating in a carboxylic acid. It is supplied as a white to off-white solid and is used for liposome and nanoparticle formulation and for surface functionalization via amide coupling.
- Terminal carboxylic acid suitable for amide coupling to primary amines.
- Average molecular weight ~2,000 Da provides PEG spacer functionality.
- Facilitates formation of stable, stealth liposomes and nanoparticles.
- White to off-white solid compatible with common organic solvents.
- High reported purity for reproducible formulation and analysis.
Medchemexpress LLC Pomalidomide-PEG4-C2-NH2 | 2225940-52-1 | 95.1% | 492.52 | 1 G
Pomalidomide-PEG4-C2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a 4-unit PEG linker, primarily utilized in PROTAC technology.
- Used in PROTAC technology
- Incorporates Pomalidomide based cereblon ligand
- Features a 4-unit PEG linker
- Target: E3 ligase ligand-linker conjugates
Medchemexpress LLC Mal-PEG4-PFP ester | 1415800-42-8 | MFCD28556926 | >98.0% | 511.39 g/mol | C21H22F5NO8 | 100 MG
Mal-PEG4-PFP ester is a non-cleavable antibody-drug conjugate (ADC) linker containing a maleimide thiol-reactive group, a four-unit polyethylene glycol (PEG4) spacer, and a pentafluorophenyl (PFP) activated ester for bioconjugation. It is supplied as a solid for research use.
- Non-cleavable maleimide PEG4 linker
- PFP ester for activated carboxyl conjugation
- Suitable for ADC and bioconjugation workflows
- Solid powder form, typically supplied at 100 mg
- Intended for research use only
Medchemexpress LLC Cholesterol-PEG-maleimide | 95.1% | 2000 (average) | 25 MG
Cholesterol-PEG-maleimide (MW 2000) is a cholesterol-terminated polyethylene glycol derivative bearing a terminal maleimide for thiol-specific conjugation. Supplied as a solid, it is intended for incorporation into liposomes and nanoparticles to provide steric stabilization and enable covalent attachment of thiol-containing ligands for surface functionalization and targeted delivery applications.
- Provides steric stabilization to liposomes and nanoparticles.
- Maleimide group enables covalent conjugation to thiols via thioether bond.
- Average PEG molecular weight 2000; polydisperse polymeric material.
- High purity (~95.1%) suitable for formulation and conjugation studies.
- Soluble in DMSO up to 100 mg/mL; freshly opened DMSO recommended.
- Powder storage: -20°C; in solvent storage recommendations included.
![eMolecules Broadpharm / Fmoc-PEG12-alcohol / 250mg / 698442899 / BP-25752 / / / [null] / 767.910 / C39H61NO14](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502475242.JPG-250.jpg)
eMolecules Broadpharm / Fmoc-PEG12-alcohol / 250mg / 698442899 / BP-25752 / / / [null] / 767.910 / C39H61NO14
Broadpharm / Fmoc-PEG12-alcohol / 250mg / 698442899 / BP-25752 / / / [null] / 767.910 / C39H61NO14
Medchemexpress LLC Mal-Ph-CONH-PEG4-NHS ester | 1263044-88-7 | 561.54 | 50 MG
Mal-Ph-CONH-PEG4-NHS ester is a non-cleavable 4 unit PEG ADC linker. It is utilized in the synthesis of antibody-drug conjugates (ADCs), which consist of an antibody attached to an ADC cytotoxin via an ADC linker.
- Non-cleavable 4 unit PEG ADC linker
- Used in the synthesis of antibody-drug conjugates (ADCs)
- Applicable as laboratory chemicals
- Suitable for the manufacture of substances
Medchemexpress LLC DSPE-PEG-DBCO sodium | 99.6% | 3400 (average) | 5 MG
DSPE-PEG-DBCO sodium (MW 3400) is a DBCO-functionalized PEGylated phospholipid supplied as a white to off-white solid. It provides a bioorthogonal DBCO handle for strain-promoted azide-alkyne cycloaddition (SPAAC) and an amphiphilic DSPE-PEG backbone suitable for incorporation into liposomes and lipid nanoparticles for surface functionalization and delivery research.
- Provides DBCO handle for copper-free click conjugation.
- Enables surface functionalization of liposomes and nanoparticles.
- Amphiphilic PEG-lipid backbone supports stable lipid formulations.
- PEG chain (average MW 3400) imparts steric stabilization and solubility.
- Supplied as a solid suitable for small-scale research use.
- Available in small packaged quantities for laboratory experiments.
Medchemexpress LLC Propargyl-PEG4-5-nitrophenyl carbonate | 1422540-81-5 | 98.2% | 397.38 | 50 MG
Propargyl-PEG4-5-nitrophenyl carbonate is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It also functions as a click chemistry reagent, featuring an Alkyne group that enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
- PEG-based PROTAC linker
- Used in PROTAC synthesis
- Click chemistry reagent
- Features an alkyne group
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide groups
- Exploits ubiquitin-proteasome system for selective protein degradation
Medchemexpress LLC M-PEG4-PFP ester | 2952895-31-5 | ≥98.0% | 402.31 | 100 MG
m-PEG4-PFP ester is a PEG-based PROTAC linker designed for use in the synthesis of PROTACs. These molecules are engineered to contain two distinct ligands, one binding to an E3 ubiquitin ligase and the other targeting a specific protein. This innovative design allows PROTACs to leverage the cell's ubiquitin-proteasome system for the selective degradation of target proteins.
- Peg-based PROTAC linker
- Used in the synthesis of PROTACs
- Contains two different ligands connected by a linker
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
Cayman Chemical BIotIn-PEG3-azIde 10mg
A PEGylated version of biotin-azide that is more hydrophilic; can be used to label terminal alkynes via copper-catalyzed click reactions or copper-free click reactions with cyclooctynes; used to covalently tag proteins in combination with other tags
Cayman Chemical dPE-PEG 2000-amInsodIum 50mg
A PEGylated derivative of DSPE; has been used in the synthesis of solid lipid and thermosensitive liposomal nanoparticles for the delivery of anticancer agents; has been used in the synthesis of fluorescein isothiocyanate-loaded mesoporous silica nanoparticles for imaging applications; can be conjugated to a variety of functional molecules for improved cellular targeting and uptake of DSPE-PEG(2000)-amine-containing nanoparticles